polysomnography
发表于 2025-3-21 20:04:03
书目名称Drug Resistance影响因子(影响力)<br> http://impactfactor.cn/2024/if/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance影响因子(影响力)学科排名<br> http://impactfactor.cn/2024/ifr/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance网络公开度<br> http://impactfactor.cn/2024/at/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance网络公开度学科排名<br> http://impactfactor.cn/2024/atr/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance被引频次<br> http://impactfactor.cn/2024/tc/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance被引频次学科排名<br> http://impactfactor.cn/2024/tcr/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance年度引用<br> http://impactfactor.cn/2024/ii/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance年度引用学科排名<br> http://impactfactor.cn/2024/iir/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance读者反馈<br> http://impactfactor.cn/2024/5y/?ISSN=BK0283116<br><br> <br><br>书目名称Drug Resistance读者反馈学科排名<br> http://impactfactor.cn/2024/5yr/?ISSN=BK0283116<br><br> <br><br>
debble
发表于 2025-3-21 21:12:50
Multidrug Resistance Associated with Overexpression of MRP of tumors, such as non-small cell lung carcinomas, this resistance is inherent, while in others (e.g., acute myelogenous leukemia) it is acquired during treatment. The problem of drug resistance has been studied in the laboratory primarily by using drug-selected, cultured tumor cell lines as model
Indict
发表于 2025-3-22 01:29:38
Mechanisms of Resistance to Alkylating Agentse result of the induction of a variety of protective mechanisms or the result of the selection of resistant clones. In some cases, neoplastic cells may also have a high intrinsic level of resistance . Alkylating agents, particularly agents that alkylate preferentially at the O6 position of guanin
提升
发表于 2025-3-22 05:01:38
Glutathione S-Transferaseschemoprotectant. In the human, levels of GSH range from 30μM in plasma to 3mM in kidney proximal tubules; tumors of various organs can contain up to 10mM GSH . GSH is synthesized via the γ-glutamyl cycle (Figure 4–1). The rate-limiting step is catalyzed by γ-glutamylcysteine synthetase (γ-GCS) to
容易做
发表于 2025-3-22 11:12:42
Role of DNA Repair in Resistance to Drugs that Alkylate O6 of Guaninents includes the methylating agents, temozolomide, procarbazine, dacarbazine (DTIC), and steptozotocin, and the chloroethylating agents, carmustine (1,3 bis-chloroethyl 2-nitrosourea, BCNU), lomustine (3-cyclohexyl-1-chloroethyl-nitrosourea, CCNU), (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarC
nerve-sparing
发表于 2025-3-22 12:56:03
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nerve-sparing
发表于 2025-3-22 18:58:26
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鞭子
发表于 2025-3-23 00:04:55
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CRASS
发表于 2025-3-23 03:26:54
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显赫的人
发表于 2025-3-23 05:38:28
Cellular Resistance to Topoisomerase Poisonstous in nature and are required for the regulation of DNA structure (topology) in the cell. Specifically, DNA topoisomerases regulate the coiling of the DNA double helix, a parameter critical for processes such as replication and transcription. Topoisomerases alter DNA coiling by transiently cleavin