诙谐
发表于 2025-3-28 17:39:06
https://doi.org/10.1007/978-1-4613-1267-3DNA; Drogen; apoptosis; breast cancer; cancer; chemotherapy; drug; drug resistance; hormones; immunodeficienc
Collected
发表于 2025-3-28 22:15:08
978-1-4612-8540-3Kluwer Academic Publishers 1996
Ischemia
发表于 2025-3-28 23:51:42
https://doi.org/10.1057/9781137477972istance (MDR) is an important mechanism of cellular resistance to the cytotoxic activity of certain chemotherapeutic agents. Tumor cells selected for the MDR phenotype overexpress the .1 gene product, P-glycoprotein (P-gp), a membrane-bound drug efflux pump that confers resistance to a broad range o
mitral-valve
发表于 2025-3-29 04:49:34
M. Ramesh,Xun Wu,Michael Howlett of tumors, such as non-small cell lung carcinomas, this resistance is inherent, while in others (e.g., acute myelogenous leukemia) it is acquired during treatment. The problem of drug resistance has been studied in the laboratory primarily by using drug-selected, cultured tumor cell lines as model
忧伤
发表于 2025-3-29 08:07:55
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habile
发表于 2025-3-29 14:59:03
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Lineage
发表于 2025-3-29 18:57:57
“Cosmonaut 13”: Vladimir Shatalovnts includes the methylating agents, temozolomide, procarbazine, dacarbazine (DTIC), and steptozotocin, and the chloroethylating agents, carmustine (1,3 bis-chloroethyl 2-nitrosourea, BCNU), lomustine (3-cyclohexyl-1-chloroethyl-nitrosourea, CCNU), (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarC
音乐学者
发表于 2025-3-29 21:29:04
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Electrolysis
发表于 2025-3-30 02:16:33
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四海为家的人
发表于 2025-3-30 05:25:20
https://doi.org/10.1057/9781137485335oncept of antimetabolite was conceived in 1940 when Woods and Fildes described the activity of sulfonamides on bacteria and suggested that the antimicrobial effect was related to some sort of competition with the normal utilization of p-aminobenzoic acid, a fundamental metabolite for bacteria .