Colonnade 发表于 2025-3-28 16:17:44
https://doi.org/10.1007/978-3-658-27654-6ly of RNA helicases and with a model bacterial system, the ATP-dependent Type III restriction-modification enzymes. Further examples are discussed and illustrate the wide-ranging examples of molecular switches in genome metabolism.伪造者 发表于 2025-3-28 20:27:49
,Tiefgaragen, Parkhäuser, Rampen,branes. The different activities required for the oriented transport of DNA across cell compartments are achieved by three separate modules within the FtsK proteins: a DNA translocation module, an orientation module and an anchoring module. In the second part of this chapter, we review the structuraAWE 发表于 2025-3-29 01:45:09
,Tiefgaragen, Parkhäuser, Rampen,operate as histone octamer-anchored directional DNA translocases in order to disrupt DNA–histone interactions and catalyze nucleosome sliding. Remodeling mechanisms are family-specific and depend on factors such as how the enzyme engages with nucleosomal and linker DNA, features of DNA loop intermedAffiliation 发表于 2025-3-29 05:15:56
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DNA Helicases in NER, BER, and MMR,) UvrD again plays a central role. The different tasks of this protein in the different repair pathways highlight the importance of regulative protein–protein interactions to fine-tune its helicase activity. In other DNA repair pathways the role of the helicases involved is sometimes not as well cha