通便
发表于 2025-3-26 20:59:27
https://doi.org/10.1007/978-1-4939-2269-7biological function; chemical; functional protein targets; in vitro cellular systems; in vitro-based com
系列
发表于 2025-3-27 04:57:26
978-1-4939-5284-7Springer Science+Business Media New York 2015
疏远天际
发表于 2025-3-27 08:54:15
http://reply.papertrans.cn/23/2243/224284/224284_33.png
身心疲惫
发表于 2025-3-27 11:56:03
1064-3745 ation advice from the experts.Includes supplementary materia.This volume seeks to enable the discovery of tools in chemical biology by providing readers with various techniques ranging from initial chemical genetic screening to target identification. To successfully highlight the essential component
果核
发表于 2025-3-27 15:45:32
https://doi.org/10.1007/978-1-4302-1603-2ulates a legion of complex chemical reactions found in intact cells. Specifically, we focus on the use of a luciferase-based fusion system to identify small-molecule modulators that affect protein turnover.
Mhc-Molecule
发表于 2025-3-27 18:40:45
http://reply.papertrans.cn/23/2243/224284/224284_36.png
Tidious
发表于 2025-3-27 23:59:01
https://doi.org/10.1007/978-1-4302-1603-2eening. Here, we describe a simple method for CLS measurement using aging minicultures in microtiter plates and batch plate-back for the determination of culture viability. This assay can be used to screen a large number of strains, conditions, or compounds in parallel for effects on aging.
有机体
发表于 2025-3-28 03:50:07
Dependency Properties and Routed Events,hput screening. NMR spectroscopy has been widely used for FBDD since it identifies and localizes the binding site of weakly interacting hits on the target protein. Here we describe ligand-based NMR methods for hit identification from fragment libraries and for functional cross-validation of primary hits.
commute
发表于 2025-3-28 10:01:18
Small-Molecule High-Throughput Screening Utilizing , Egg Extractulates a legion of complex chemical reactions found in intact cells. Specifically, we focus on the use of a luciferase-based fusion system to identify small-molecule modulators that affect protein turnover.
Galactogogue
发表于 2025-3-28 10:24:50
http://reply.papertrans.cn/23/2243/224284/224284_40.png