使成核 发表于 2025-3-28 17:30:25
Proteome Integral Solubility Alteration (PISA) for High-Throughput Ligand Target Deconvolution withe. PISA dramatically reduces analysis costs, allowing many research questions in need of target deconvolution to be addressed, and unlocks the potential of miniaturizing biological models, including primary cells.critic 发表于 2025-3-28 22:09:42
Biophysical Approaches for the Characterization of Protein-Metabolite Interactions,tate-of-the-art biophysical toolbox for the study of protein-metabolite interactions. It briefly introduces basic principles, highlights recent examples from the literature, and pinpoints promising future directions.FATAL 发表于 2025-3-28 23:22:38
,Identification of Plant Protein–Metabolite Interactions by Limited Proteolysis-Coupled Mass Spectroparation is performed including a complete digestion with the sequence-specific protease trypsin. Finally, label-free proteomics analysis is applied to identify structure-dependent proteolytic patterns corresponding to protein targets of the specific metabolite and their binding sites. Given its ame我们的面粉 发表于 2025-3-29 03:38:27
Detecting and Characterizing Interactions of Metabolites with Proteins by Saturation Transfer Diffenteractions of natural products and metabolites, in particular. The reader is also referred to excellent reviews of the field and the literature cited therein. This chapter also provides a detailed experimental protocol for performing the STD NMR measurement based on the example of the subunit A of使熄灭 发表于 2025-3-29 10:45:24
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https://doi.org/10.1007/978-3-319-67308-0nteractions of natural products and metabolites, in particular. The reader is also referred to excellent reviews of the field and the literature cited therein. This chapter also provides a detailed experimental protocol for performing the STD NMR measurement based on the example of the subunit A of