MEDAL
发表于 2025-3-21 18:19:49
书目名称Antifolate Drugs in Cancer Therapy影响因子(影响力)<br> http://figure.impactfactor.cn/if/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy影响因子(影响力)学科排名<br> http://figure.impactfactor.cn/ifr/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy网络公开度<br> http://figure.impactfactor.cn/at/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy网络公开度学科排名<br> http://figure.impactfactor.cn/atr/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy被引频次<br> http://figure.impactfactor.cn/tc/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy被引频次学科排名<br> http://figure.impactfactor.cn/tcr/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy年度引用<br> http://figure.impactfactor.cn/ii/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy年度引用学科排名<br> http://figure.impactfactor.cn/iir/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy读者反馈<br> http://figure.impactfactor.cn/5y/?ISSN=BK0158545<br><br> <br><br>书目名称Antifolate Drugs in Cancer Therapy读者反馈学科排名<br> http://figure.impactfactor.cn/5yr/?ISSN=BK0158545<br><br> <br><br>
drusen
发表于 2025-3-21 22:36:43
Ekphrasis and the Polytemporal in w antifolate drugs approved for marketing: trimetrexate (Neutrexin), a lipophilic inhibitor of dihydrofolate reductase (DHFR) for treatment of the life-threatening fungal infection, . pneumonia; and the thymidylate synthase (TS) inhibitor, raltitrexed (Tomudex), for colorectal cancer. In addition to
expeditious
发表于 2025-3-22 04:25:03
https://doi.org/10.1057/9780230370531s of folate metabolism, alterations in the activity of any folate enzyme, cellular transport system, as well as the concentration of any folate metabolite may be relevant to antifolate cytotoxicity and selectivity. Therefore, it is difficult to predict the results of inhibiting a given folate enzyme
军火
发表于 2025-3-22 08:15:26
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尖叫
发表于 2025-3-22 10:40:44
Die Prurigoformen flüchtigeren CharaktersTX, .) were found to induce temporary remission in children with acute leukemia .. In the five decades that followed this landmark in the history of chemotherapy ., the term “an-tifolate” or “antifol” has come to refer not only to inhibitors of DHFR but also to in-hibitors of other enzymes of one-ca
一个搅动不安
发表于 2025-3-22 13:15:57
Die Prurigoformen flüchtigeren Charaktersombination with other agents for the treatment of various types of cancer . such as cancers of the gas-trointestinal tract, breast cancer, and head and neck cancer. For combinations of leucov-orin (LV) and 5FU objective response rates between 20 and 40% have been achieved in randomized trials in pat
STALL
发表于 2025-3-22 18:25:02
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HIKE
发表于 2025-3-22 23:17:21
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Hot-Flash
发表于 2025-3-23 02:51:43
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为敌
发表于 2025-3-23 06:43:04
C. Guillén,M. C. Romero,I. Galindote moieties in vivo. However, unlike some other TS inhibitors and other antifolates, the TS inhibition constant and noncompetitive mode of inhibition is unaffected by polyglutamation. The compound is readily transported on the reduced folate carrier, and accumulates in cells. The main cellular metab