Dictation 发表于 2025-3-26 21:42:35
https://doi.org/10.1007/978-3-476-99282-6ators have been developed. However, doxorubicin andclosely related anthracyclines still remain among the most effective antitumor agents. Multiple mechanismshave been proposed to explain their efficacy. They include inhibition of DNA-dependent functions, freeradical formation, and membrane interacti制定法律 发表于 2025-3-27 04:42:50
http://reply.papertrans.cn/16/1583/158257/158257_32.pnghankering 发表于 2025-3-27 07:16:46
http://reply.papertrans.cn/16/1583/158257/158257_33.png出没 发表于 2025-3-27 11:31:47
http://reply.papertrans.cn/16/1583/158257/158257_34.png障碍物 发表于 2025-3-27 15:24:10
Einführung in die Analyse von Prosatexten tumor site while releasing the cytotoxic drug..Among immuno-conjugates representing a widely studied class of doxorubicin derivatives,the clinical development of cBR96-Dox, undoubtedly the most quintessential derivative, was discontinueddue to severe secondary effects. More potent cBR-96 analogueslethal 发表于 2025-3-27 20:56:34
https://doi.org/10.1007/978-3-476-98966-6raquinones, and as such are redox active. Their redoxchemistry leads to induction of oxidative stress and drug metabolites. An intermediate in reductive glycosidiccleavage is a quinone methide, once proposed as an alkylating agent of DNA. Subsequent research nowimplicates formaldehyde as a mediator掺假 发表于 2025-3-28 01:04:09
https://doi.org/10.1007/978-3-476-98966-6-aminated sugar, namely 2-deoxy-.-rhamnose or 2-deoxy-.-fucose andthe second moiety is daunosamine, have been obtained upon synthesis of the appropriate activated sugarintermediate and glycosylation of the corresponding aglycones. The compounds containing 2-deoxy-.-fucose exhibit superior pharmacoloMammal 发表于 2025-3-28 06:01:29
http://reply.papertrans.cn/16/1583/158257/158257_38.pngFantasy 发表于 2025-3-28 07:16:32
10楼无王时期, 发表于 2025-3-28 14:14:26
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