驼峰 发表于 2025-3-21 17:42:48

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流眼泪 发表于 2025-3-21 23:56:52

,The Genetics of Alzheimer’s Disease,r’s disease as occurring in the presenium. The same neuropathological changes occurring in brains over the age of 65 were called “senile dementia.” Because there have been no clinical or pathological features to separate the two groups, this somewhat arbitrary distinction has been abandoned. Althoug

Cardioplegia 发表于 2025-3-22 01:15:24

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gimmick 发表于 2025-3-22 06:08:00

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dictator 发表于 2025-3-22 12:38:12

,Quantifying Aβ1–40 and Aβ1–42 Using Sandwich-ELISA,ecursor protein (APP) that alter Aβ production are linked to a subset of familial AD (FAD) cases with autosomal penetrance (reviewed in .. .). Several of these FAD-associated APP mutations, as well as FAD-associated mutations in the presenilin 1 (PS1) and presenilin 2 (PS2) genes, lead to an increas

切碎 发表于 2025-3-22 15:09:03

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growth-factor 发表于 2025-3-22 19:54:23

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incredulity 发表于 2025-3-22 23:18:14

,Effects of the β-Amyloid Peptide on Membrane Ion Permeability, electrophysiological techniques that can be employed to isolate and record specific membrane conductances that may be altered by Aβ. In general, an increase in conductances that cause depolarization of the cell membrane may be considered excitotoxic since they will: (.) increase Ca.influx through v

遗留之物 发表于 2025-3-23 04:53:56

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拘留 发表于 2025-3-23 08:08:18

Posttranslational Modifications of Amyloid Precursor Protein,ail (.). Translation of APP occurs at the endoplasmic reticulum (ER) and the protein is translocated into the ER lumen. The N-terminal domain of APP is directed towards the luminal compartment of the ER, whereas the C-terminal domain faces the cytoplasm. After synthesis, APP passes from the ER to th
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查看完整版本: Titlebook: Alzheimer‘s Disease; Methods and Protocol Nigel M. Hooper Book 2000 Humana Press 2000