Inclement 发表于 2025-3-30 10:07:50
http://reply.papertrans.cn/16/1543/154257/154257_51.png商议 发表于 2025-3-30 13:01:31
http://reply.papertrans.cn/16/1543/154257/154257_52.png转向 发表于 2025-3-30 20:20:42
Posttranslational Modifications of the Amyloid Precursor Protein,er provides methods for analyzing the glycosylation of APP that is actively synthesized by living cells in tissue culture. These methods can be applied to primary cultures, continuous cell lines, and transfected cell lines expressing recombinant APP.medium 发表于 2025-3-30 21:45:08
,Development of Neoepitope Antibodies Against the β-Secretase Cleavage Site in the Amyloid Precursorptide from APP (. .). More routine identification of the secretase activities has relied on the specificity and sensitivity of antibodies raised to the predicted cleavage products and has been impeded by the difficulties associated with the generation of such reagents.incite 发表于 2025-3-31 01:49:37
http://reply.papertrans.cn/16/1543/154257/154257_55.pngSynapse 发表于 2025-3-31 05:32:17
http://reply.papertrans.cn/16/1543/154257/154257_56.png粗野 发表于 2025-3-31 11:26:04
https://doi.org/10.1007/978-3-662-02210-8 cleavages govern the level of Aβ generated from the amyloid precursor protein (APP). β- and γ-cleavages at the amino and carboxyl termini of Aβ produce amyloidogenic peptides; in contrast, α-cleavage within the Aβ domain destroys the amyloidogenic potential of APP. The proteases responsible for these cleavages have not been identified.countenance 发表于 2025-3-31 16:08:16
http://reply.papertrans.cn/16/1543/154257/154257_58.pngImpugn 发表于 2025-3-31 19:07:42
http://reply.papertrans.cn/16/1543/154257/154257_59.pnglegitimate 发表于 2025-3-31 23:55:14
http://reply.papertrans.cn/16/1543/154257/154257_60.png