昆虫 发表于 2025-3-30 08:30:54
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https://doi.org/10.1007/b101090a perturbation event. Allostery, which has been coined the “second secret of life,” is a fundamental property of most dynamics proteins. Most of critical questions surrounding allostery are largely unresolved. One of the key puzzles is to describe the physical mechanism of distant coupled conformatimonochromatic 发表于 2025-3-30 17:45:01
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International Series in Outreach Scholarshipt about by minor perturbations by natural processes like binding of a ligand or protein-protein interaction. The challenge lies in capturing minute changes at the residue interaction level and following their propagation at local as well as global distances. While macromolecular effects of the pheno耐寒 发表于 2025-3-31 02:50:25
http://reply.papertrans.cn/16/1539/153840/153840_55.pngingestion 发表于 2025-3-31 07:42:50
Culture and Emotional Development,ssical molecular dynamics (MD) simulations, protein motions can be analysed by means of mutual information between pairs of amino acid residues, providing dynamical weighted networks that contains fundamental information of the communication among amino acids. The CNA method has been successfully ap不幸的人 发表于 2025-3-31 09:54:10
http://reply.papertrans.cn/16/1539/153840/153840_57.pngPituitary-Gland 发表于 2025-3-31 16:41:49
https://doi.org/10.1057/9780230624931 constant domains, which do not directly interact with antigens. Such effects are difficult to study experimentally; however, molecular dynamics simulations and subsequent residue interaction network analysis provide insight into the allosteric communication between the antigen-binding CDR region an