Autobiography 发表于 2025-3-25 06:48:54
Oligomerization of Retrovirus Integrases,on is carried out by integrase (IN), a virus-encoded enzyme that forms an oligomeric ‘intasome’ complex with both ends of the linear viral DNA to catalyze their concerted insertions into the backbones of the host’s DNA. IN also forms a complex with host proteins, which guides the intasome to the hosPalate 发表于 2025-3-25 10:13:11
,Structure and Function of the Human Respiratory Syncytial Virus M2–1 Protein,espiratory tract infection worldwide, responsible for up to 199,000 deaths each year. The only FDA-approved regime to prevent HRSV-mediated disease is pre-exposure administration of a humanized HRSV-specific monoclonal antibody, which although being effective, is not in widespread usage due to its cCHASM 发表于 2025-3-25 13:58:33
Filamentous Bacteriophage Proteins and Assembly,igms in structural molecular biology and offer insight into molecular assembly, a process that remains to be fully understood. In this chapter, an overview on filamentous bacteriophages will be provided. In particular, we review the constituent proteins of filamentous bacteriophage and discuss assem冲突 发表于 2025-3-25 18:50:32
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The Bacteriophage Head-to-Tail Interface,of the viral genetic information to the host cell at the beginning of infection. In tailed bacteriophages, the portal system is connected to a tail device that delivers their genome to the bacterial cytoplasm. The head-to-tail interface is a multiprotein complex that locks the viral DNA inside the p好忠告人 发表于 2025-3-26 00:45:45
Beyond Channel Activity: Protein-Protein Interactions Involving Viroporins,ers, disrupting the physiology of the host to the advantage of the virus. Consequently, efforts during the last few decades have been focused towards the discovery of viroporin channel inhibitors, but in general these have not been successful to produce licensed drugs. Viroporins are also involved iarrhythmic 发表于 2025-3-26 06:09:53
Protein Complexes and Virus-Like Particle Technology,at controlled conditions. Therefore, the basic knowledge about the mechanisms of viral particle formation is highly important for designing of industrial applications. As an alternative to genetic and chemical processes, different physical methods are frequently used for VLP construction, including思考而得 发表于 2025-3-26 10:38:23
The Role of Flaviviral Proteins in the Induction of Innate Immunity,Zika virus, West Nile virus, Japanese encephalitis virus, and Dengue virus have the potential to cause severe disease. Extensive studies have been performed to elucidate the structure and replication strategies of flaviviruses, and current studies are aiming to unravel the complex molecular interactLATHE 发表于 2025-3-26 13:39:12
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0306-0225 and function.Written by acknowledged experts in their field..The Subcellular Biochemistry series has recently embarked upon an almost encyclopaedic coverage of topics relating to the structure and function of macromolecular complexes (Volumes 82, 83 and 87). The present multi-author text covers nume