摊位
发表于 2025-3-28 15:29:35
Visualization by nlsLacZ of Gene Activity During Mouse Embryogenesis,rulation. From these progenitors, many distinct cell types develop during the next few days. Their probable number is far greater than the number of described histological cell types. When the embryo progenitor cells are determined the genome has been epigenetically modified. Indeed, the male and fe
大火
发表于 2025-3-28 20:17:34
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ALT
发表于 2025-3-29 02:17:57
Mutations in Transgenic Mice,r human hereditary diseases but also permits a systematic genetic dissection of the mammalian genome. In mammals, three approaches have been successful in inducing mutations (Gridley et al., 1987; Jaenisch, 1988): (i) infection of preimplantation mouse embryos with retroviruses, (ii) microinjection
Silent-Ischemia
发表于 2025-3-29 05:55:56
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glucagon
发表于 2025-3-29 08:33:50
Cellular Target Sequences for Retrovirus Integration,d host cell. Although central to the retroviral life cycle and decisive for many of the biological and pathological consequences of a retrovirus infection, the molecular events involved in the integration process are only partly understood. Viral DNA synthesis by reverse transcription and the struct
Crayon
发表于 2025-3-29 14:15:00
Identification of Retroviral Sequences Involved in the Inactivation of the Viral Genome in Embryona viral genome to accommodate foreign DNA sequences combined with its ability to infect a wide variety of cells make retroviruses an attractive system for gene transfer. However, the use of retroviruses to introduce and express foreign genes in mouse preimplantation embryos has been hampered because
不幸的人
发表于 2025-3-29 17:50:46
Strand Switching During Retroviral Reverse Transcription,genome into a linear double stranded DNA copy. A principal area of research in our lab has centered on template switching during reverse transcription and the consequences of this translocation depending on whether switching occurs intermolecularly or intramolecularly. For these studies we have exam
我邪恶
发表于 2025-3-29 23:07:14
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卷发
发表于 2025-3-30 01:30:25
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放大
发表于 2025-3-30 04:25:30
Cell Targeting by Recombinant Retroviruses Using Bi-Specific Antibody Complexes,d successfully to infect human cells with ecotropic murine retroviruses via the interaction with MHC class I and class II antigens. The sequential protocol we developed requires less stringent safety constraints than would handling of amphotropic virus stocks. Although its efficiency is still relati