BRUNT 发表于 2025-3-23 11:18:19
Targeted Delivery of Antisense Oligonucleotides and siRNAs into Mammalian Cells,ll interfering RNA (siRNAs) can be delivered in vitro to virtually all cell types using lipid-based transfection agents or electroporation, efficient strategies for achieving either systemic or targeted delivery remains one of the major in vivo challenges. Among the targeting strategies, receptor-ta座右铭 发表于 2025-3-23 14:43:56
http://reply.papertrans.cn/89/8854/885381/885381_12.png公理 发表于 2025-3-23 20:39:54
Imaging of siRNA Delivery and Silencing,he efficiency of target gene silencing. The molecular imaging approach fits perfectly to fulfill these needs and provides information in a fast, reproducible, and noninvasive manner. This review serves as a first attempt to summarize existing information on various imaging modalities and their appliMendacious 发表于 2025-3-23 23:37:02
http://reply.papertrans.cn/89/8854/885381/885381_14.png山崩 发表于 2025-3-24 06:19:35
http://reply.papertrans.cn/89/8854/885381/885381_15.pngSubstitution 发表于 2025-3-24 06:35:22
Bacterial Delivery of siRNAs: A New Approach to Solid Tumor Therapy,RNAi-based therapies has been slow due to the lack of targeted delivery methods. The biggest challenge in the use of siRNA-based therapies is delivery to target cells. There are many additional obstacles to in vivo delivery of siRNAs, such as degradation by endogenous enzymes and interaction with bl警告 发表于 2025-3-24 13:32:32
http://reply.papertrans.cn/89/8854/885381/885381_17.png展览 发表于 2025-3-24 15:57:20
pSM155 and pSM30 Vectors for miRNA and shRNA Expression,liferation, and organ development. miRNAs regulate gene function through a process termed RNA interference (RNAi), which is a highly conserved intracellular mechanism that regulates posttranscriptional gene silencing. RNAi is triggered by double-stranded small interfering RNAs (siRNAs), which can becanonical 发表于 2025-3-24 22:33:37
http://reply.papertrans.cn/89/8854/885381/885381_19.pngslipped-disk 发表于 2025-3-25 01:03:25
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