吹牛大王 发表于 2025-3-23 11:29:56
MicroRNA Regulated Stress Responses in Cancer,ere are thousands of microRNAs, each regulating hundreds to thousands of protein’s expression levels, and this review serves to elucidate the nature of microRNAs through selected examples suggesting potential therapeutic opportunities.侵蚀 发表于 2025-3-23 14:13:16
Senescence in Oncogenesis: From Molecular Mechanisms to Therapeutic Opportunities, other stimuli, such as oncogenic stress, DNA damage or cytotoxic drugs. These non-proliferative characteristics prompted the scientists to look for therapies that can induce the senescent phenotype in tumor cells as therapeutic approach.通便 发表于 2025-3-23 18:03:44
Integrating Proteotoxic Stress Response Pathways for Induction of Cell Death in Cancer Cells: Molec cancer. Cancer cells can up-regulate signaling associated with the UPR to promote growth and resist anti-cancer therapy. Knowledge of the mechanism associated with the UPR may provide novel therapeutic targets for cancer therapy.无节奏 发表于 2025-3-23 22:41:54
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p53 at the Crossroads Between Stress Response Signaling and Tumorigenesis: From Molecular Mechanismion of specific target genes. p53 activation triggers a variety of cellular responses that ensure tumor suppression, including cell cycle arrest, apoptosis and senescence. In addition, p53 tumor suppressive activity also involves the maintenance of cellular homeostasis through the regulation of metastrain 发表于 2025-3-24 22:53:59
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MicroRNA Regulated Stress Responses in Cancer,aced with two options—adapt or perish. Their responses are usually the manifestation of complex molecular signaling cascades, which are attempting to maintain cellular homeostasis despite the increasingly harsh environment. These signaling cascades are fine-tuned through constant monitoring and regu