刺穿 发表于 2025-3-27 00:46:54
Antigenic Variation and Immune Escape in the MTBC,establish infection. Highly successful microbial pathogens, including ., are able to evade adaptive immune responses (mediated by antibodies and/or T lymphocytes) and thereby establish long-term chronic infection. One mechanism that diverse pathogens use to evade adaptive immunity is antigenic variabackdrop 发表于 2025-3-27 03:57:23
PE and PPE Genes: A Tale of Conservation and Diversity,me. The most ancestral PE and PPE proteins are expressed by genes that belong to the same operon and in most cases are found inserted in the . clusters, encoding a type VII secretion system. Duplication and expansion of . and . genes, coupled with intragenomic and intergenomic recombination events,BROW 发表于 2025-3-27 06:21:12
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Evolution of Phenotypic and Molecular Drug Susceptibility Testing,pt diagnosis followed by an appropriate treatment should be provided to patients. Phenotypic DST based on liquid automated culture has greatly reduced the time needed to generate reliable data but has the drawback to be expensive and prone to contamination in the absence of appropriate infrastructurbonnet 发表于 2025-3-27 15:02:58
DNA Replication Fidelity in the , Complex, strains of the . complex. When considered in the context of the specific features of the disease . causes (e.g., transmission via cough aerosol, replication within professional phagocytes, subclinical persistence, and stimulation of a destructive immune pathology), this implies that to understand tetiquette 发表于 2025-3-27 19:49:32
Strain Diversity and the Evolution of Antibiotic Resistance,er to be relevant to human health. In this context, genetic diversity can influence the rate and likelihood of resistance emerging; it can also modulate the net physiological impact of resistance and the propensity of an organism to improve any defects that arise from it. Combined, these effects canabracadabra 发表于 2025-3-28 01:10:02
Mathematical Models for the Epidemiology and Evolution of ,,troduce general epidemiological models, and describe their use with respect to epidemiological dynamics of a single strain and of multiple strains of .. In particular, we discuss multi-strain models that include drug sensitivity and drug resistance. Second, we describe models for the evolution of .角斗士 发表于 2025-3-28 03:33:39
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