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0070-217X bility to mount an effective humoral immune response against foreign antigens. The immune system must maintain a balance between the deletion of harmful self-reactive B cells and the generation of a diverse rep ertoire of B cells that has the ability to recognize an almost un limited array of fore惰性女人 发表于 2025-3-22 01:07:20
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Signal Transduction via the B-cell Antigen Receptor: The Role of Protein Tyrosine Kinases and Proteession of the membrane immunoglobulin heavy chain of the BCR in conjunction with pseudo- light-chain gene products is essential for establishing allelic exclusion and for promotion of gene recombination at the light-chain loci. Subsequent expression of a mature BCR complex on the surface of immaturetendinitis 发表于 2025-3-22 13:27:11
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Intermediary Signaling Effectors Coupling the B-Cell Receptor to the Nucleus,s. These tyrosine kinase substrates include proteins involved in the activation of key signal-trans- duction pathways. The role of these signaling pathways is to convey the signal from the BCR to cellular targets. These targets include: (1) transcription factors that regulate the expression of genes忙碌 发表于 2025-3-22 22:30:13
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