Expediency 发表于 2025-3-23 10:15:20
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Cancer Dose-Response Models Incorporating Clonal Expansion,of mathematical models of carcinogenesis that have a potential to be used for cancer dose-response modeling are discussed. The two classes of models considered are (1) a general version of the two-stage model by Moolgavkar and colleagues , henceforth called the MVK model, and (2) a clone pro空洞 发表于 2025-3-24 06:52:06
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Interindividual Variation in Human Chemical Carcinogenesis: Implications for Risk Assessment,tumor suppressor genes. Chemical carcinogens are generally activated enzymatically to electrophiles that form covalently bound carcinogen-DNA adducts. Detoxifying enzymes are competing with the activating enzymes for these procarcinogenic chemical substrates. Wide person to person variations in thes预测 发表于 2025-3-25 02:06:09
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