甜食 发表于 2025-3-23 09:54:59

Bioavailability Under the Prism of Finite Absorption Timebed in terms of FAT. Explicit relationships are derived for the bioavailable fraction as a function of the model parameters assuming one-compartment model disposition with zero- or first-order absorption lasting for a certain period of time. An application using a theophylline example is presented. Extent and rate metrics are reinterpreted.

反叛者 发表于 2025-3-23 14:10:52

Bioequivalence Under the Prism of Finite Absorption Timetric for the extent of drug absorption. This concept was successfully applied to two published bioavailability digoxin studies. The cumulative ratio of areas as a function of sampling time is suggested as a diagnostic test and criterion for the assessment of the drug’s extent of absorption.

值得赞赏 发表于 2025-3-23 19:13:10

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bronchiole 发表于 2025-3-24 01:20:33

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Deduct 发表于 2025-3-24 02:59:00

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Sputum 发表于 2025-3-24 07:31:18

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Lipoma 发表于 2025-3-24 12:18:36

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疼死我了 发表于 2025-3-24 17:58:03

978-3-031-20027-4The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

不自然 发表于 2025-3-24 22:26:26

Revising Oral Pharmacokinetics, Bioavailability and Bioequivalence Based on the Finite Absorption Ti

圆柱 发表于 2025-3-25 00:50:42

Revising Oral Pharmacokinetics, Bioavailability and Bioequivalence Based on the Finite Absorption Ti978-3-031-20025-0
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查看完整版本: Titlebook: Revising Oral Pharmacokinetics, Bioavailability and Bioequivalence Based on the Finite Absorption Ti; Panos Macheras,Athanasios A. Tsekour