browbeat 发表于 2025-3-30 08:26:59
http://reply.papertrans.cn/83/8293/829208/829208_51.pngMystic 发表于 2025-3-30 15:52:43
Sophia-Martha kleine Holthaus,Alexander J. Smith,Sara E. Mole,Robin R. AliAspirin 发表于 2025-3-30 17:43:17
Mitochondria: Potential Targets for Protection in Age-Related Macular Degenerationcan lead to the chronic oxidative stress associated with the disease. Therefore, one protective strategy may involve the use of small molecule therapies that target the regulation of mitochondrial biogenesis and mitochondrial fission and mitophagy.JOG 发表于 2025-3-30 22:25:10
Toll-Like Receptors and Age-Related Macular Degenerationof membrane-spanning PRRs for which host-derived ligands have been identified; these include heat shock proteins, extracellular matrix breakdown products, mRNA from necrotic cells and modified lipids. Here we review the evidence for TLR involvement in the pathogenesis of AMD.彩色 发表于 2025-3-31 03:23:11
Alterations in Extracellular Matrix/Bruch’s Membrane Can Cause the Activation of the Alternative ComE)/Bruch’s membrane (BrM), which favors the anchoring of complement C3b generated by convertase-independent cleavage of C3 via tick-over and produces a chronic activation of the alternative complement pathway.Throttle 发表于 2025-3-31 06:45:54
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Estimations of Retinal Blue-Light Irradiance Values and Melatonin Suppression Indices Through Clear r the +10-D, +20-D, and +30-D ZCB00V IOLs, respectively; 1.03 for phakic eyes; and 1.21 for aphakic eyes. The data from the six clear IOLs (SA60AT, Alcon Japan; VA-60BBR, Hoya; AU6 K, Kowa, N4-18B, Nidek; X-60, Santen; KS-3Ai, Staar Japan) and seven yellow-tinted IOLs (SN60AT; YA-60BBR, Hoya; AU6N,天气 发表于 2025-3-31 15:46:43
Mini-Review: Cell Type-Specific Optogenetic Vision Restoration Approachesich is indicated by clinical studies with epiretinal implants, where patients can perform simple visual tasks. Finally, optogenetics in combination with neuroprotective approaches could serve as a valuable strategy to restore the function of remaining cells, as well as to rescue retinal neurons fromadj忧郁的 发表于 2025-3-31 20:22:22
Optimizing Non-viral Gene Therapy Vectors for Delivery to Photoreceptors and Retinal Pigment Epitheld that our particles are flexible enough to sustain changes in the formulation to accommodate additional targeting sequences without losing their efficiency in transfecting neuronal cells in the retina. Together, these results give us the opportunity to even further improve our particles.