记成蚂蚁
发表于 2025-3-23 10:17:52
http://reply.papertrans.cn/83/8285/828459/828459_11.png
idiopathic
发表于 2025-3-23 15:10:23
Role of P-Glycoprotein for Resistance of Tumors to Anticancer Drugs: From Bench to Bedside,ouse tumor lines, we investigated inherent drug resistance in human lung xenograft tumors transplanted to nude mice. Drug resistance in these xenografts was also associated with overexpression of P-glycoprotein and . mRNA, but without . gene amplification. Furthermore, we explored P-glycoprotein exp
collateral
发表于 2025-3-23 20:27:42
Clinical Relevance of Multidrug-Resistance-Proteins (MRPs) for Anticancer Drug Resistance and Prognibute directly to drug resistance based on in vivo models and patient data. We will also discuss the value of MRP expression as a prognostic marker and its potential role in selecting treatment protocols and examine existing and novel strategies to target MRPs.
ERUPT
发表于 2025-3-24 01:32:44
A New Strategy of ALA-Photodynamic Cancer Therapy: Inhibition of ABC Transporter ABCG2, target genes, including those for metabolizing enzymes and transporters essential for cellular defense. Whereas Nrf2 upregulates transcription of the . gene to confer cancer cells resistance, several protein kinase inhibitors reportedly interfere with the transport function of ABCG2. In fact, gefit
PET-scan
发表于 2025-3-24 02:20:45
http://reply.papertrans.cn/83/8285/828459/828459_15.png
结束
发表于 2025-3-24 08:54:25
http://reply.papertrans.cn/83/8285/828459/828459_16.png
Lipohypertrophy
发表于 2025-3-24 11:48:51
ABC Transporter Modulatory Drugs from Marine Sources: A New Approach to Overcome Drug Resistance in patients. Overcoming this pathway of resistance with the use of modulators to block the drug efflux transporters has shown some promise in recent years. However, there is still room for improvement in designing the clinical strategy and developing newer agents to overcome MDR. Nature has provided r
carotid-bruit
发表于 2025-3-24 16:29:41
The Role of ABC Multidrug Transporters in Resistance to Targeted Anticancer Kinase Inhibitors,hanism of TKI action. In this review, we present the key TKIs currently used in cancer therapy, and discuss their interactions with MDR-ABC transporters. We also describe the methods for studying various forms of direct MDR-ABC and TKI interactions, and present a framework for understanding a comple
顶点
发表于 2025-3-24 23:02:56
Drugs Affecting Epigenetic Modifications of ABC Transporters for Drug Resistance,igenetic modifications of the genes have been emerging as a part cause of ABC transporter-mediated drug resistance. In this chapter, therefore, epigenetic modifications of the ABC transporter genes are covered, where the outlines of the regulatory mechanisms and factors involved in the epigenetic mo
CHAR
发表于 2025-3-25 00:46:40
http://reply.papertrans.cn/83/8285/828459/828459_20.png