BUCK 发表于 2025-3-26 21:44:33
CD4+Foxp3+Regulatory T Cells in Immune Tolerance-occurring CD4. Treg cells (nTreg) represent a major lymphocyte population maintaining dominant self-tolerance and controlling a variety of pathological immune responses. These nTreg cells specifically express Foxp3, a transcription factor that plays a critical role in their development and functionfaculty 发表于 2025-3-27 02:29:34
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CD4+CD25+ Regulatory T Cells as Adoptive Cell Therapy for Autoimmune Disease and for the Treatment oeveloped therapeutic approaches to tackle systemic and organ-specific autoimmune diseases, and treatment with general immunosupressants may soon be replaced by novel therapies based upon this research. Recently, interest in the field of regulatory T cells along with accumulated information that thesCumulus 发表于 2025-3-27 10:57:21
Natural CD4,CD25, Regulatory T Cells in Regulation of Autoimmune Diseaseign antigens. However, one inevitable consequence of TCR diversity is the generation of self-reactive TCRs creating the potential for autoimmune disease. To balance this, the immune system has developed the processes of central and peripheral tolerance to deter the generation of self-reactive T cell弹药 发表于 2025-3-27 15:05:23
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CD4+CD25+ Regulatory T Cells and TGF-Beta in Mucosal Inflammation. Indeed the abrogation of the TGF-beta signaling in immune cells leads to autoimmunity and inflammation in several organs including the gut. TGF-beta acts at multiple levels to maintain the immune system in check. However, TGF-beta has been recently shown to play a key role in the peripheral genera子女 发表于 2025-3-27 23:17:01
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Regulatory T Cells in Transplantationugs to inhibit immune responses. These approaches require life-long treatment and suppress the entire immune system non-specifically exposing the patient to increased risks of cancer and infection. Even then long-term graft survival is not guaranteed. Evidence that regulatory T cells can control rej清楚说话 发表于 2025-3-28 09:04:27
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