Cacophonous
发表于 2025-3-25 07:04:11
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背书
发表于 2025-3-25 08:45:49
Chang-Hun Kim,Sun-Jeong Kim,Soo-Kyun Kim,Shin-Jin Kangchanism beyond genes that can be inherited through cell divisions. Proper development of the embryo involves a multilayer regulation of gene expression to ensure proper temporal and spatial control of expression of genes. This precise control of gene expression translates to initiation and maintenan
incontinence
发表于 2025-3-25 14:25:53
Chang-Hun Kim,Sun-Jeong Kim,Soo-Kyun Kim,Shin-Jin Kang (i) the mechanisms that regulate the spatio-temporal replication program, and (ii) the links between origins activation, chromatin structure and transcription. In this chapter, we review the partitioning of the human genome into megabased-size replication domains delineated as N-shaped motifs in th
paradigm
发表于 2025-3-25 18:28:54
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Host142
发表于 2025-3-25 20:03:50
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臆断
发表于 2025-3-26 02:05:58
and fertilization of an egg. Germ cells are unique in their capability to generate new organisms, and extra caution has to be taken to secure the correct inheritance of genetic and epigenetic information. Male germ cells are epigenetically distinct from somatic cells and they undergo several importa
neutralize
发表于 2025-3-26 05:21:47
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勤劳
发表于 2025-3-26 08:51:00
Chang-Hun Kim,Sun-Jeong Kim,Soo-Kyun Kim,Shin-Jin Kangf therapies targeting epigenetic modifiers have been approved by the FDA for cancer treatment, and many others are in clinical trials. Ongoing research is focused on better understanding mechanisms contributing to the altered epigenome, how the altered epigenome contributes to malignant transformati
cogitate
发表于 2025-3-26 15:22:36
Chang-Hun Kim,Sun-Jeong Kim,Soo-Kyun Kim,Shin-Jin Kang biomarker γH2AX: from bench science to clinicaltrials.What’sthe risk? Dental amalgam, mercury exposure, and human health risksthroughout the lifespan.Post-traumatic stress disorder:neurological, genetic, and epigenetic bases.Children’s exposure to alcohol, tobacco, and drugs:long-term outcomes.Ethi
AVERT
发表于 2025-3-26 20:34:52
Chang-Hun Kim,Sun-Jeong Kim,Soo-Kyun Kim,Shin-Jin Kangand plasticity in the cells to give rise to proper tissues in the embryo. The key features mentioned above are imparted by epigenetic mechanisms that exist in the embryo. There are three major epigenetic mechanisms that cells use to establish and maintain their epigenetic states, namely, a specific