龙虾
发表于 2025-3-26 21:27:33
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说笑
发表于 2025-3-27 05:02:50
Principles of Dicer Substrate (D-siRNA) Design and Functionhetic 21-mer siRNAs, suggesting a coupling of the Dicer-mediated processing step to the efficient assembly of the silencing complex, RISC. We describe the fundamental principles and experimental results leading to optimal Dicer substrates.
Laconic
发表于 2025-3-27 08:39:46
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进取心
发表于 2025-3-27 11:50:48
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Lament
发表于 2025-3-27 15:46:59
Identifying siRNA-Induced Off-Targets by Microarray Analysisp of the human genome. To achieve this, small interfering RNAs (siRNAs), short synthetic duplexes having complete homology to the intended target, are introduced into cells to silence gene expression via a posttranscriptional cleavage mechanism. While siRNAs can be designed to effectively knock down
altruism
发表于 2025-3-27 19:30:10
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Vo2-Max
发表于 2025-3-27 23:45:49
Nasal Delivery of siRNAut chemical modifications can be applied intranasally. Various delivery vehicles have been tested and optimized. With a few exceptions, all promote significant uptake of siRNA into the lung tissue and offer protection against respiratory viruses such as respiratory syncytial virus (RSV), parainfluen
Commonwealth
发表于 2025-3-28 05:10:54
RNA Interference as a Genetic Tool in Trypanosomese carried out ., making this a powerful means for the study of protein function . Several trypanosomatids, including those organisms responsible for human and animal diseases, naturally possess the machinery necessary for RNAi manipulations. This allows for the use of RNAi in unraveling many of the
暗讽
发表于 2025-3-28 09:11:13
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epicardium
发表于 2025-3-28 10:25:28
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