obsession 发表于 2025-3-23 12:41:35
Regulation of Osteoblast Differentiation by Runx2, Runx2 is the first transcription factor required for determination of the osteoblast lineage, while Sp7 and canonical Wnt-signaling further direct the fate of mesenchymal cells to osteoblasts, blocking their differentiation into chondrocytes. Runx2 induces the differentiation of multipotent mesench控诉 发表于 2025-3-23 17:13:13
Communication Between EphrinB2 and EphB4 Within the Osteoblast Lineage,Production of ephrinB2 mRNA and protein are increased by PTH and PTHrP in osteoblasts. Both a synthetic peptide antagonist of ephrinB2/EphB4 receptor interaction and recombinant soluble extracellular domain of EphB4 (sEphB4), which is an antagonist of both forward and reverse EphB4 signaling, were aannexation 发表于 2025-3-23 20:08:38
The Unexpected Link Between Osteoclasts and the Immune System,particular, the interaction between immune cells and osteoclasts is a current major topic of critical interest in this field. The macrophage-osteoclast interaction has long been studied, and the T-cellosteoclast interaction also attracted much attention in the study of arthritis. However, recent rep云状 发表于 2025-3-24 01:39:49
NFATc1 in Inflammatory and Musculoskeletal Conditions, particular, is crucial to multiple seemingly unrelated biologic processes, including heart valve formation, T-cell activation, osteoclast development, and the mitigation of hair follicle stem cell proliferation. Here, we review how our recently generated NFATc1 conditional knockout mouse has contri痛恨 发表于 2025-3-24 03:49:47
Novel Functions of RANK(L) Signaling in the Immune System,ly, and have been shown to augment the ability of DCs to stimulate naive T cell proliferation and enhance DC survival. Since another, yet soluble receptor for RANKL, namely OPG, was initially characterized as a factor inhibiting osteoclast development and bone resorption, it was somewhat enigmatic aBlanch 发表于 2025-3-24 09:14:10
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ls of sufficient sophistication to address complex intergene.This textbook explores sustainability, climate change, and the corporate responsibility movement from a broad array of perspectives, including the challenges, risks, and opportunities of ESG policies, energy and environmental science, econ