Mundane
发表于 2025-3-23 13:09:22
Leucovorin as a Prodrugizes the inhibitory ternary complex formed between the FU active metabolite, FdUMP and thymidylate synthase, resulting in suppression of DNA synthesis or repair.. It has been demonstrated both in animal models. and in humans. that administration of leucovorin results in intratumor elevation of CH.FH
树木中
发表于 2025-3-23 17:40:35
Clinical Use of Leucovorin: Intracellular Metabolismand upper aerodigestive system. While many analogs of 5-fluorouracil have been synthesized since the early 1960’s none has supplanted 5-fluorouracil for general clinical use. One of the major focal points of recent investigative work has been efforts to enhance the activity of 5-fluorouracil through
Heart-Attack
发表于 2025-3-23 19:15:48
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清洗
发表于 2025-3-24 00:07:40
Effects of 5-Fluorouracil on mRNAcols which are dependent upon 5-fluorouracil (FU). The basis for this interest rests largely upon the exquisite sensitivity of the enzyme to the antimetabolite 5-fluorodeoxyuridylate, the demonstration of numerous cell culture effects which can be explained by enzyme inhibition, and increased tumor
品牌
发表于 2025-3-24 04:21:17
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EVEN
发表于 2025-3-24 09:22:24
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拱形面包
发表于 2025-3-24 12:10:13
5-Fluorouracil Combined with the Pure -Stereoisomer of Folinic Acid in High Doses for Treatment luorouracil (5-FU) and fluorodeoxyuridine (FUdR)] . (1,2,3). Potentiation of the antitumor activity of 5-FU by folinic acid has been demonstrated in patients with gastrointestinal carcinomas (4–10); this has resulted in effective palliative treatment for patients with advanced colorectal adenocarcin
间谍活动
发表于 2025-3-24 17:34:46
5-Fluorouracil Modulation in Colorectal Carcinoma Experience of German Investigators of FU. Among the modulating agents folinic acid (FA) has been proven to increase response rates, while its impact on patients survival is still questionable.. Nevertheless FU in combination with FA is considered by most oncologists as standard treatment in advanced stages of colorectal cancer. Its
Meditate
发表于 2025-3-24 22:34:36
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到婚嫁年龄
发表于 2025-3-24 23:48:38
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