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Cancer Prevention by Different Forms of Tocopherols,large-scale human trials with high doses of α-tocopherol (α-T) have produced disappointing results. This points out the need for a better understanding of the biological activities of the different forms of tocopherols. Using a naturally occurring tocopherol mixture (γ-TmT) that is rich in γ-T, we d发炎 发表于 2025-3-22 00:59:12
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A Perspective on Dietary Phytochemicals and Cancer Chemoprevention: Oxidative Stress, Nrf2, and Epims in cells. ROS/RNS or carcinogen metabolites can attack intracellular proteins, lipids, and nucleic acids, which can result in genetic mutations, carcinogenesis, and other diseases. Nrf2 plays a critical role in the regulation of many antioxidative stress/antioxidant and detoxification enzyme gene预定 发表于 2025-3-22 15:53:39
,Keap1–Nrf2 Signaling: A Target for Cancer Prevention by Sulforaphane,ar targets in cellular and animal models; however, amongst the most sensitive is Keap1, a key sensor for the adaptive stress response system regulated through the transcription factor Nrf2. Keap1 is a sulfhydryl-rich protein that represses Nrf2 signaling by facilitating the polyubiquitination of Nrfintangibility 发表于 2025-3-22 21:05:13
Chemoprotection Against Cancer by Isothiocyanates: A Focus on the Animal Models and the Protective hioglucosidase enzymes (myrosinases). The Cruciferae family represents a rich source of glucosinolates. Notably, nearly all of the biological activities of glucosinolates, in both plants and animals, are attributable to their cognate hydrolytic products, and the isothiocyanates are prominent example口诀 发表于 2025-3-23 01:10:10
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