Discrete
发表于 2025-3-30 09:00:20
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BLUSH
发表于 2025-3-30 15:55:19
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accomplishment
发表于 2025-3-30 19:25:43
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considerable
发表于 2025-3-30 22:23:02
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PRISE
发表于 2025-3-31 01:06:42
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行业
发表于 2025-3-31 06:27:04
Assessing the ATP Binding Ability of NLRP3 from Cell Lysates by a Pull-down Assay,ing is followed after elution from the beads and detection with Western blot and immunolabelling. The method can be used to evaluate the functionality of NLRP3 variants or to check whether compounds or NLRP3 binding partners interfere with binding of ATP.
neuron
发表于 2025-3-31 11:04:51
Inflammasome-Independent Roles of NLR and ALR Family Members,ers exert inflammasome-independent functions. Here, we will discuss inflammasome-independent functions of NLRC4, NLRP12, and AIM2 and examine their roles in regulating innate and adaptive immune processes.
椭圆
发表于 2025-3-31 15:49:30
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独裁政府
发表于 2025-3-31 20:26:17
Theoretical 3D Modeling of NLRP3 Inflammasome Complex,n structural modeling that provides unique insights into the biological role and activation of NLRP3 oligomer. Finally, the same approach can be easily adapted to the rest of the members of the NLRP family.
人类的发源
发表于 2025-3-31 21:45:05
Methods to Measure NLR Oligomerization I: Size Exclusion Chromatography, Co-immunoprecipitation, an the oligomeric state with high sensitivity and stability. ASC oligomerization has been successfully used as readout for NLR/ALR inflammasome activation in response to various PAMPs and DAMPs in human and mouse macrophages and THP-1 cells. Here, we provide a detailed description of the methods used