悄悄移动
发表于 2025-3-23 12:53:36
Pierre Dustinamme in the early 1960‘s, the expectation was that the retinoids would have a major impact on oncology. However, the laboratory and clinical experiences of Bollag and his colleagues in Switzerland, Stuttgen and Orfanos in Germany, led to publications on both etretinates (Tigason) and isotretinoin (R
光明正大
发表于 2025-3-23 16:15:25
Pierre Dustinhan inductive reasoning. Because of this it is not infrequent that we are presented with compounds that are therapeutically effective but whose mode of action remains mysterious. It is worthwhile bearing in mind that it is only in the past 20 or 30 years that we have understood how digitalis and mor
Anticoagulant
发表于 2025-3-23 18:06:21
Pierre Dustindifficulties are presented by bullous ichthyosiform erythroderma (syn. epidermolytic hyperkeratosis) and by non-bullous ichthyosiform eyrthro-derma (syn. lamellar ichthyosis). Intensive topical therapy with emollients and keratolytics provides only limited and short-lived relief in the worst affecte
DALLY
发表于 2025-3-24 00:47:54
Pierre Dustinhan inductive reasoning. Because of this it is not infrequent that we are presented with compounds that are therapeutically effective but whose mode of action remains mysterious. It is worthwhile bearing in mind that it is only in the past 20 or 30 years that we have understood how digitalis and mor
Soliloquy
发表于 2025-3-24 04:12:17
http://reply.papertrans.cn/64/6336/633559/633559_15.png
悲痛
发表于 2025-3-24 08:51:32
Acknowledgments,ble without the facilities available at the University of Brussels. My warmest thanks go to my secretary, Mrs. D. Libert, who not only typed the final manuscript, but also checked my text for inaccuracies or repetitions, and helped considerably in the preparation of the lists of references. Througho
替代品
发表于 2025-3-24 14:02:47
Structure and Chemistry of Microtubules, weight. The shape and properties of MT proceed from the linkages of these two closely related molecules. However, other proteins appear to be necessary for tubulin assembly into MT or may become closely linked with MT when these assemble into complex structures such as centrioles, basal bodies, cil
可能性
发表于 2025-3-24 15:57:47
General Physiology of Tubulins and Microtubules,tubulin in the formation of far more complex organelles, like centrioles and cilia, and the effects of various drugs on MT, some fundamental data about general aspects of MT physiology will be considered: the synthesis of tubulins in the cell; its regulation; the role of nucleating sites for the ass
发酵
发表于 2025-3-24 19:33:26
http://reply.papertrans.cn/64/6336/633559/633559_19.png
Cytology
发表于 2025-3-25 01:32:58
Microtubule Poisons,reventing its assembly into MT. It is now indispensable to give further details about the action of these drugs, and of other chemicals which may have, under various conditions, similar effects. In the next chapters, colchicine and other poisons will often be mentioned, in relation to cell movements