Blasphemy
发表于 2025-3-30 08:40:06
the important nucleic acid-based therapies to treat neurodegenerative diseases along with the opportunities and challenges depending on the disease and the drug target. In addition, we will also accentuate the present-day application of these inhibitory small RNAs and antisense oligonucleotides in a
chisel
发表于 2025-3-30 13:32:20
ol, it is important to elucidate how riboswitches interact with cognate and discriminate against non-cognate ligands. Here we outline the methodology to synthesize riboswitch RNAs and prepare riboswitch–ligand complexes for crystallographic and biochemical studies. The chapter describes how to desig
indices
发表于 2025-3-30 19:36:00
g phase determination through molecular replacement of conserved Fab domains. Major steps described in this chapter include selection of a synthetic Fab library displayed on M13 phage against a structured RNA crystallization target, ELISA for initial choice of binding Fabs, Fab expression followed b
hematuria
发表于 2025-3-30 22:07:02
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郊外
发表于 2025-3-31 02:30:59
reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.. .Authoritative and practical, .Nucleic Acid Chemistry: Methods and Protocols .seeks to aid scientists in the further study of detection for DNA and RNA..978-1-4939-6041-5978-1-62703-535-4Series ISSN 1064-3745 Series E-ISSN 1940-6029