ODE 发表于 2025-3-21 19:39:07
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Mario Marcelo Berón,Hernán Bernardis,Enrique Alfredo Miranda,Daniel Edgardo Riesco,Maria João Varand平常 发表于 2025-3-22 10:48:51
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Recent in vivo studies unequivocally have proven that the stabilization of mutant p53 is crucial pre-requisite for its oncogenic functions. The pharmacological targeting the pathways involved in the stabilization of mutant p53, in particular, the Hsp90 chaperone complex, recently attracted a lot of来就得意 发表于 2025-3-22 18:42:40
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Alberto Simões,José João Almeidaecent evidence to suggest these inhibitors have indications as antiviral drugs. This chapter aims to highlight the roles of HSP70 and HSP90 in the lifecycle of numerous viruses. Furthermore, this will highlight the potential for already developed HSP70 and HSP90 inhibitors as antivirals and the deve