Organonitrile 发表于 2025-3-23 13:46:37
Marco Vicente,Joao P. Carvalho,Fernando Batista heat shock protein (HSP90) is required for the conformational maturation and stability of a variety of proteins in multiple pathways, such as epidermal growth factor receptor (EGFR), AKT, Raf, cdk4, etc. Therefore, an HSP90 inhibitor may show therapeutic benefit in TNBC by targeting multiple pathwa试验 发表于 2025-3-23 15:31:13
Marcos Garcia,Pablo Gamallold become a novel, effective therapeutic target. This possibility is discussed both in the light of negative chaperonotherapy, namely the development of means to inhibit HSP60 in the event its excessive activity is a disease-promoting event in AD, as well as positive chaperonotherapy, that is boosti散步 发表于 2025-3-23 19:50:49
Furthermore, in ovarian cancer cells HSP27 is required for metastasis upon MET activation in vivo and modulates the sensitivity to the first line chemotherapeutics Cisplatin and Paclitaxel. Altogether, these findings suggested that HSP27 induction by targeted agents might impact the success of targNUL 发表于 2025-3-23 22:29:05
Hugo Correia,António Menezes Leitãoe of bovine tuberculosis [.]. Apart from the fact that MB and MAP have different tissue trophisms, they share many other characteristics. Both cause slow developing diseases, with a long asymptomatic period during which disease is spread between individuals, eventually causing a wasting syndrome in泥土谦卑 发表于 2025-3-24 06:07:26
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João Cruz,Pedro Rangel Henriques,Daniela da Cruzgen species (ROS) scavengers, as well as act synergistically with the antioxidant system. These small proteins also play a key role in maintaining membrane quality attributes, including fluidity and permeability under chilling stress. Membrane damage and ROS production are multifaceted adverse effec同步信息 发表于 2025-3-24 15:07:09
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