magnify 发表于 2025-3-21 18:16:13
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Influence of Physical and Environmental Factors on Ion Channels in Arterial Musclefor the transduction of physical and environmental influences with respect to vascular reactivity is activation or inhibition of ion conductance systems setting a level of membrane potential around which vascular tone is enhanced or reduced.使厌恶 发表于 2025-3-22 04:19:05
An ATP-Activated Potassium Channel in Smooth Muscle Cells from the Pulmonary Arteryoreceptors, so experiments on single smooth muscle cells from pulmonary vessels, backed up by complementary experiments on isolated vessels and lungs, are likely to be the most successful way forward.predict 发表于 2025-3-22 06:36:03
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Role of Calcium ATPases in Pulmonary Vascular Reactivity: plasma membrane (PM) Ca. pumps (130–150 kd) and sarcoplasmic or endoplasmic reticulum (SER) Ca. pumps (100–115 kd) (12, 16, 17). The PM Ca. pumps along with Na./Ca. exchange are the major mechanisms for Ca. extrusion from the cell. The SER Ca.-ATPase pumps buffer an increase in . by reloading intracellular stores with Ca. (16, 36).圆桶 发表于 2025-3-22 21:23:05
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Calcium Channels in Arterial Smooth Muscle Cellstrongly suggest that calcium entry through dihydropyridine-sensitive calcium channels is necessary for maintained tone development in many cases, and that the membrane potential dependence of arterial tone arises from the voltage-dependence of the calcium channel (12).挑剔为人 发表于 2025-3-23 06:50:09
sely and to document the opening and closing of individual ion channels has provided a powerful tool to those working on smooth muscle physiology and vascular reactivity. The use of potassium channel blockers by Tom Lloyd in the 1960s and calcium channel blockers by Ivan McMurtry in the 1970s indica