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,The Role of Endogenous Interferon-α in HIV Infection and Autoimmune Diseases—An Overview,In the course of HIV infection, the role of interferon-α (IFN-α) seems to be rather paradoxical: “It is possible to view alpha-IFN as either a therapeutical agent or as a major contributor to the pathology associated with AIDS.” (S. Krown, 1992).欲望小妹 发表于 2025-3-22 13:07:59
,Use of Interferon-α in the Treatment of Chronic Myelogenous Leukemia,Chronic myelogenous leukemia (CML) is a clonal disease of hematopoietic stem cells . It is characterized by an excessive increase in granulopoiesis and frequently also in megakaryopoiesis. The diagnostic criteria may vary slightly between authors and countries but in general include:祸害隐伏 发表于 2025-3-22 18:46:11
,Distribution of Interferon-α2 Genes in Humans,ells and the nature of the infecting virus. Over the past 20 years it has become clear that there are many forms of IFNs produced. They can be grouped into four IFN families based upon their similarities and differences: alpha, beta, gamma, and omega IFNs. As shown in Table 1, only the alpha-interfe仪式 发表于 2025-3-22 23:00:51
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Interferon Therapy of Neuroendocrine Tumours,res and, not least, improved treatment, the number of cases has increased during the last two decades. The first case was described already in 1902 by Oberndorfer, who introduced the term . for a less malignant neoplasm. The incidence of patients with clinically significant carcinoid tumours is 0.5/minion 发表于 2025-3-23 06:08:12
Interferon Therapy of Essential Thrombocythemia and Polycythemia Vera,ineage bone marrow hyperplasia, whereas in essential thrombocythemia (ET), proliferation of the megakaryocytic lineage prevails. Both diseases run a relatively benign clinical course, and survival is almost normal. Morbidity and mortality result primarily from vascular complications, i.e., thromboem