Merited
发表于 2025-3-30 11:52:13
Introduction: Motivations for Next-Generation ADCs,innovations of next-generation ADCs described throughout the volume. A framework for designing and interpreting preclinical pharmacology studies is proposed such that emerging technologies can be rigorously evaluated and molecules can be judiciously optimized.
下垂
发表于 2025-3-30 16:01:13
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无法治愈
发表于 2025-3-30 19:38:24
Targeting Drug Conjugates to the Tumor Microenvironment: Probody Drug Conjugates,making antibody prodrugs that have been or could be used to selectively deliver drug to a tumor compared to normal tissues. These technologies have the potential to lower on-target, off-tumor toxicities and enable better efficacy of ADCs due to better target selection and the delivery of higher concentrations of drug to tumors.