Kindle
发表于 2025-3-26 22:42:58
Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activitytors of certain PPP-family phosphatases. The review will focus on two compounds, cantharidin and fostriecin, addressing discovery, molecular mechanisms of action, affects on cultured cell, clinical use, toxicity, plasma pharmacokinetics, and a brief review of data from a phase I human clinical trial.
floodgate
发表于 2025-3-27 02:06:42
Clinical Aspects of Imatinib Therapythus far. Clinical trials with imatinib were expanded and there are now examples of malignancies driven by each of the targets of imatinib where remarkable results have been seen. The rationale for the use of imatinib in these various diseases and the clinical trial results will be reviewed.
你敢命令
发表于 2025-3-27 06:09:35
0171-2004 of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles. .978-3-642-42206-5978-3-540-26670-9Series ISSN 0171-2004 Series E-ISSN 1865-0325
系列
发表于 2025-3-27 11:26:56
Inhibitors of PKA and Related Protein Kinasesm the AGC group and the cocrystallization of these ersatz kinases with small molecules as well as cocrystal structures of other AGC kinases like 3-phosphoinositide-dependent kinase 1 (PDK1) with staurosporine and bisindolylmaleimide derivatives helps in the identification and exploration of factors governing selectivity.
conceal
发表于 2025-3-27 15:14:13
0171-2004 otein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum
eucalyptus
发表于 2025-3-27 21:11:10
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极大的痛苦
发表于 2025-3-28 00:46:56
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bacteria
发表于 2025-3-28 03:36:31
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Catheter
发表于 2025-3-28 08:21:52
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Handedness
发表于 2025-3-28 12:41:55
Inhibitors of Protein Kinase CK2: Structural Aspectsby its ability to use both ATP and GTP as co-substrates and the low susceptiveness to staurosporine inhibition. On the basis of three-dimensional crystal structures, we describe and discuss the effects of the binding to CK2 of inhibitors with a potency in the low micromolar range belonging to differ