背信
发表于 2025-3-23 13:15:02
Why do Homocysteine Levels increase?,iseases and drugs can, directly or indirectly, disturb Hcy metabolism. Therefore, in most cases, elevated homocysteine levels are not caused by a single factor, but are the result of a cluster of factors, fig. 8.
overbearing
发表于 2025-3-23 14:02:41
Clinical Impact of Enzyme Defects,ne β-synthase (CBS) gene, over 90 mutations have been identified so far. A few of these, often fairly common mutations, increase the enzyme activity, and thereby reduce tHcy levels. Others reduce the activity and may have a synergistic tHcy-increasing effect with, for instance, the C677T polymorphism.
AWE
发表于 2025-3-23 21:55:05
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Customary
发表于 2025-3-24 01:14:01
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令人不快
发表于 2025-3-24 02:46:53
Introduction,The importance of homocysteine as a risk factor or risk marker is becoming a familiar concept. Since the early 1990s a constantly increasing number of studies have been published on homocysteine. It has also been the topic of three international conferences, in 1995, 1998, and 2001.
Classify
发表于 2025-3-24 08:25:33
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新义
发表于 2025-3-24 13:35:46
Homocysteine Metabolism,Homocysteine is metabolised through two major pathways: transsulphuration and methylation. Normally, about 50% is re-methylated to form methionine, from which it originally derives.
Accolade
发表于 2025-3-24 16:27:36
How can Homocysteine be Neurotoxic?,The proposed pathogenetic mechanisms, by which hyperhomocysteinemia may cause vascular damage, cognitive impairment, psychiatric and neurological complications, congenital defects, and pregnancy complications, converge.
fructose
发表于 2025-3-24 19:00:48
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恶心
发表于 2025-3-25 03:00:38
How to interpret the Test Results and how to handle Hyperhomocysteinemia?,Each laboratory uses a central 95% reference range based upon results from a general population. The reference limits are generally within the range of 5 and 13–15 µmol/L.