飞来飞去真休
发表于 2025-4-1 03:53:12
The Use of Human Hepatocytes to Investigate Drug Metabolism and CYP Enzyme Induction, Major problems were linked to poor metabolic stability and drug–drug interactions linked to inhibition or induction of metabolism. Since most small molecule (MW below 1000) drugs are cleared from the body by the liver, primary cultures of human hepatocytes became the most predictive and widely used
强化
发表于 2025-4-1 09:26:33
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Adrenaline
发表于 2025-4-1 10:51:38
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抛媚眼
发表于 2025-4-1 17:46:12
Metabonomic Studies on Human Hepatocyte in Primary Culture,etry-based metabonomics as a global investigation tool. Sample preparation to data analysis have been detailed in an approach enabling to separate drug-induced (endogenous metabolites) and drug-related (drug metabolites) biomarkers for reference inducers. Rifampicin, a nuclear pregnane X receptor (P
Vulnerary
发表于 2025-4-1 18:51:37
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