照相机 发表于 2025-3-21 19:49:33

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感情脆弱 发表于 2025-3-21 21:32:01

Eiichi IshiiDescribe the pathogenesis and treatment of several representative hematological disorders in children.Special focus on the genetic and molecular aspects of childhood hematological disorders.Broadens r

obviate 发表于 2025-3-22 01:36:39

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BOON 发表于 2025-3-22 06:08:00

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易于 发表于 2025-3-22 10:56:10

Hematopoietic Stem Cells: The Basis of Normal and Malignant Hematopoiesisd transit through several different tissues, including the yolk sac, aorta-gonad-mesonephros (AGM) region, placenta, and fetal liver, before colonizing in the bone marrow where they reside throughout the individual’s life. HSCs, characterized by the ability to self-renew and generate all types of bl

清楚说话 发表于 2025-3-22 14:53:15

Acute Lymphoblastic Leukemiak-stratified multi-agent chemotherapy through cooperative clinical trials worldwide, survival rate of childhood ALL increased from less than 10% in the 1960s to approximately 90% nowadays. Recent advance in genomic analyses is rapidly increasing our understanding of the pathobiology of ALL, which ma

Glaci冰 发表于 2025-3-22 21:04:03

Acute Myeloid Leukemiaes, survival rates have currently reached approximately 70% in de novo AML and 80% in myeloid leukemia associated with Down syndrome and acute promyelocytic leukemia (APL). Advance in genomic analyses would contribute to further understanding of the pathobiology of AML, which is expected to result i

切割 发表于 2025-3-22 21:41:01

Myelodysplastic Syndrome (MDS) and Juvenile Myelomonocytic Leukemia (JMML)e proportion of blasts in the bone marrow (BM) and peripheral blood, it is divided into low-grade MDS and advanced MDS. Low-grade MDS often shows hypocellular BM, which makes differentiation from aplastic anemia and inherited bone marrow failure syndrome challenging. Treatment strategy for low-grade

厌食症 发表于 2025-3-23 04:51:45

Neutropenia (In Infancy and Childhood)00/μL. Chronic neutropenia in pediatric patients is divided into three groups. Extrinsic factors, such as antibodies, some drugs, and nutritional deficiencies, lead to excessive destruction of neutrophils. Autoimmune neutropenia is a benign form of neutropenia shown in infancy to early childhood. Sp

Infiltrate 发表于 2025-3-23 06:25:35

Childhood Aplastic Anemias. Of note, development of the next-generation sequencing has identified minor clones and novel somatic mutations in AA. As a result, clonal hematopoiesis in AA has become widely recognized. The mechanism of disease progression from AA to myelodysplastic syndrome/acute myelogenous leukemia has been
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查看完整版本: Titlebook: Hematological Disorders in Children; Pathogenesis and Tre Eiichi Ishii Book 2017 Springer Nature Singapore Pte Ltd. 2017 Childhood.Infant.M