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Mouse Models of Type 2 Diabetes,genic pathogenesis. To dissect the complex genetics of insulin resistance and beta cell dysfunction, investigators have generated transgenic and knock-out mice bearing various mutations in genes required for insulin action and/or insulin secretion. This chapter reviews recent progress in the field and analyzes outstanding questions.confide 发表于 2025-3-22 05:39:07
1566-0729 d geneticists who seek to learnmore about this rapidly changing and important field. The textcontains chapters from experts in the area who review aspects of thegenetics of both type 1 and 2 diabetes mellitus as well as varioussyndromic forms of diabetes. The chapters are approachable for thosewho a眼界 发表于 2025-3-22 10:58:46
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https://doi.org/10.1007/978-3-662-29157-3ing hyperglycemia occurs when impaired islet ß-cell function results in an underproduction of insulin relative to the prevailing insulin sensitivity (.). This chapter aims to provide the basis for the understanding of ß-cell function measurements . as much as this can be useful in unraveling the genetic basis of type 2 diabetes.LIEN 发表于 2025-3-22 18:42:11
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Genetics of Complex Diseases, the insulin gene for type 1 diabetes (.–.) and apolipoprotein E for late-onset Alzheimer’s disease (.–.), few genes have been confirmed to have a functional role in the etiology of complex human disease. However, newer developments in molecular methodologies make the prospects of finding complex dicoagulate 发表于 2025-3-23 06:27:01
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