instill 发表于 2025-3-27 00:05:28
Book 1992nd mouth disease viruses, and Newcastle disease virus. During the past decade, it has become clear that most, it not all. , RNA viruses (riboviruses and retroviruses) are much more mutable than was recognized previously, and that this great mutability generates extremely complex populations consistiNEEDY 发表于 2025-3-27 03:52:21
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https://doi.org/10.1007/978-3-663-13664-4ating new organisms best able to survive in the environment that surrounds them. Survival within an exceptionally hostile environment might be favored by populations containing a wide spectrum of pre-existing mutants that provide a diverse repertoire for selection.occurrence 发表于 2025-3-27 15:04:54
RNA Virus Populations as Quasispecies,viruses. For example, the mutation rate of bacteriophage T4 approximates 10. per base pair per replication (. 1969). However, some DNA viruses may avoid high-fidelity replication mechanisms (. et al. 1969; . et al. 1984) to gain the evolutionary advantages of high mutation frequencies (. and . 1987).lipids 发表于 2025-3-27 21:06:17
Selection of Zidovudine-Resistant Variants of Human Immunodeficiency Virus by Therapy,apy in humans has selected for drug-resistant variants of influenza A virus, herpes simplex virus, varicella zoster virus, cytomegalovirus and rhinovirus (. 1990). The prospect of drug resistance to zidovudine (AZT) therefore did not appear as a surprise to many.轻而薄 发表于 2025-3-27 23:01:10
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