蚊子
发表于 2025-3-30 10:03:07
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Allodynia
发表于 2025-3-30 12:22:02
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ALIEN
发表于 2025-3-30 17:20:50
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TRUST
发表于 2025-3-30 20:41:11
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送秋波
发表于 2025-3-31 04:37:38
h-throughput use, in an effort to inactivate all genes in the mouse genome. Gene trapping is performed with vectors that simultaneously inactivate and report the expression of the trapped gene and provide a molecular tag for its rapid identification. Gene-trap approaches have been used successfully
Ebct207
发表于 2025-3-31 05:52:21
Levels of Analysis: The Inter-state Levelr phenotypically neutral. To understand the genetic consequences of such genomic changes, these mutations need to be modelled in experimentally tractable systems. The mouse is an excellent organism for this analysis because of its biological and genetic similarity to humans, the ease with which its
agenda
发表于 2025-3-31 10:12:52
https://doi.org/10.1007/978-94-017-1031-2lls. However, oligonucleotide-directed substitution, insertion or deletion of a single or a few nucleotides was hampered by DNA mismatch repair (MMR). We have developed strategies to circumvent this problem based on findings that the central MMR protein MSH2 acts in two different mismatch recognitio
我没有命令
发表于 2025-3-31 13:30:29
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得意人
发表于 2025-3-31 20:29:36
hnologies to manipulate the genome, plus its developmental and physiological similarities to humans, it has become a goal to generate mutations in all mouse genes and analyze the phenotypic consequences. Gene targeting in embryonic stem (ES) cells is the method of choice for making null mutations in
痛恨
发表于 2025-4-1 00:25:03
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