抱负 发表于 2025-3-26 21:30:03

https://doi.org/10.1007/978-3-658-30820-9esents our method and offers tips for evaluating G protein signaling in endogenous tissues. Predominately, brain tissues are discussed here; optimization points that can be applied to any tissues are highlighted.

侵害 发表于 2025-3-27 02:08:32

https://doi.org/10.1007/978-3-658-08454-7in this chapter can be applied to other members of the DREADD family and, of course, different cell types. It is likely that the use of DREADD technology will identify physiologically important signaling pathways that can be targeted for therapeutic purposes.

墙壁 发表于 2025-3-27 06:33:03

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乳汁 发表于 2025-3-27 09:58:54

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痴呆 发表于 2025-3-27 16:40:24

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adequate-intake 发表于 2025-3-27 18:12:52

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MELD 发表于 2025-3-28 00:56:05

High-Throughput Screening for Allosteric Modulators of GPCRs,ram. The identification of allosteric modulators, in particular, poses significant challenges for HTS. We describe several HTS protocols designed for the identification of GPCR ligands, with a particular focus on the identification of allosteric modulators.

树木心 发表于 2025-3-28 03:21:50

2001 Mars Odyssey Mission Summary,ation on the overall architecture and dynamics of protein complexes. Here we provide a concise protocol for negative stain imaging and two-dimensional (2D) projection analysis of GPCR complexes, including notes for the intricacies of the application in these biological systems.

一个姐姐 发表于 2025-3-28 09:13:46

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充满人 发表于 2025-3-28 13:54:49

2D Projection Analysis of GPCR Complexes by Negative Stain Electron Microscopy,ation on the overall architecture and dynamics of protein complexes. Here we provide a concise protocol for negative stain imaging and two-dimensional (2D) projection analysis of GPCR complexes, including notes for the intricacies of the application in these biological systems.
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查看完整版本: Titlebook: G Protein-Coupled Receptors in Drug Discovery; Methods and Protocol Marta Filizola Book 2015Latest edition Springer Science+Business Media