让空气进入 发表于 2025-4-1 02:49:30

A Time-Resolved Fluorescent Lanthanide (Eu)-GTP Binding Assay for Chemokine Receptors as Targets inir receptors have been implicated in several disease processes, particularly inflammatory and autoimmune disorders and cancer, and are therefore attractive targets for drug development. Chemokine receptors are members of the seven-transmembrane, G protein-coupled receptor (GPCR) family. As such they

thalamus 发表于 2025-4-1 07:10:50

Use of the DiscoveRx Hithunter cAMPII Assay for Direct Measurement of cAMP in Gs and Gi GPCRs,n be employed to detect agonists (inverse, partial, and full) in addition to allosteric and classical orthosteric antagonists. Several different homogenous assay systems can be used to monitor the signaling cascades of GPCRs. This chapter details the authors’ collective experience of using the Disco

祖传财产 发表于 2025-4-1 13:47:56

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查看完整版本: Titlebook: G Protein-Coupled Receptors in Drug Discovery; Wayne R. Leifert Book 2009 Humana Press 2009 Calcium.Cellular signalling.Chemokine.Drug dev