传家宝
发表于 2025-3-21 17:08:21
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终点
发表于 2025-3-21 23:03:54
Vesicle- and Hepatocyte-Based Assays for Identification of Drug Candidates Inhibiting BSEP Functionsubstrate signal can be determined in the cells and bile or the cells alone, respectively. Performing this assay in the presence and absence of potentially interfering compounds of interest enables exploration of the relative effect of these compounds on biliary excretion of the probe substrate.
placebo-effect
发表于 2025-3-22 00:47:28
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多产鱼
发表于 2025-3-22 06:35:16
In Vivo Measurement of Hepatic Drug Transporter Inhibition with Radiolabeled Bile Acids,sporters in mice, using the nuclear imaging techniques positron emission tomography and single photon emission computed tomography. The protocol includes detailed information on preparation of the animal, scan acquisition, processing, and (statistical) analysis.
Cleave
发表于 2025-3-22 09:09:26
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frozen-shoulder
发表于 2025-3-22 13:11:23
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frozen-shoulder
发表于 2025-3-22 18:23:15
Transcriptomic Analysis of Cholestatic Compounds In Vitro,r repeat exposure-related toxicities, as well as for the study of adaptive responses. This primary human hepatocyte culture system combined with transcriptomics carries the future promise to identify individual gene expression profiles predictive of increased drug-induced cholestasis risk..This chap
Digest
发表于 2025-3-22 23:18:41
System Microscopy of Stress Response Pathways in Cholestasis Research,having cholestasis liability and affected genes during cholestatic injury on cellular adaptive stress pathway activation. The approach involves high-throughput live-cell visualization of GFP-tagged key proteins of the oxidative stress response/Nrf2 pathway and inflammatory cytokine signaling. Quanti
RADE
发表于 2025-3-23 04:04:15
1064-3745 .Experimental Cholestasis Research. serves as an ideal guide for basic andapplied researchers pursuing this vital area of research in pharmacology and toxicology..978-1-4939-9422-9978-1-4939-9420-5Series ISSN 1064-3745 Series E-ISSN 1940-6029
无法破译
发表于 2025-3-23 06:06:38
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