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Glutamate in Neurodegenerative Disorders: Phenotype Resulting from Decreased Expression of AMPA Rechin this locus is controlled by posttranscriptional RNA editing (Sommer et al. 1991). Transgenic mice engineered to synthesize unedited GluR-B subunits express Ca.permeable AMPA receptors. These mice develop progressive neurodegeneration and spontaneous seizures (Brusa et al. 1995).接合 发表于 2025-3-22 01:21:55
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Conference proceedings 1998 Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotectiohemoglobin 发表于 2025-3-22 15:23:31
0947-6075 discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neurhemoglobin 发表于 2025-3-22 18:30:50
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Quantitative Estimation of NMDA Receptor-Mediated Ca2+ Entry in Central Neurons,forms of synaptic plasticity (Bliss and Collingridge 1993; Malenka and Nicoll 1993), as well as excitatotoxicity (Lipton 1993; Mody and MacDonald 1995) and programmed cell death (Bonfoco et al. 1995; Qin et al. 1996). Ca. entry through activated NMDA receptors has been suggested to be involved in the triggering of all of these processes.