Rinne-Test
发表于 2025-3-28 14:58:34
https://doi.org/10.1057/9780230348936 drugs have been developed that are progressing rapidly in oncology clinical trials. This chapter provides an overview of EGFR inhibitors and key clinical trial results that are helping to define a future role for these molecular agents in cancer treatment.
Moderate
发表于 2025-3-28 19:54:26
Epidermal Growth Factor978-1-59745-012-6Series ISSN 1064-3745 Series E-ISSN 1940-6029
原始
发表于 2025-3-29 02:21:27
A Historical Perspective of the EGF Receptor and Related Systems,been shown to have various effects on numerous cellular systems. The biological and physiological role that EGF plays during development and in adult animals led to the identification of its receptor (EGFR) as well as the other members of the EGF family of growth factors and their receptors. In this
平庸的人或物
发表于 2025-3-29 03:47:56
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grandiose
发表于 2025-3-29 08:11:08
Soluble Epidermal Growth Factor Receptor Acridinium-Linked Immunosorbent Assay,nked immunosorbent assay (ALISA) developed by Baron and coworkers (.). This ALISA has been shown to be specific for epidermal growth factor receptor (EGFR) and the isoforms of EGFR encoded by alternate transcripts (i.e., sEGFRs); it, therefore, does not detect other EGFR/ErbB receptor family members
不自然
发表于 2025-3-29 13:55:15
,Analysis of EGF Receptor Interactions With the α Subunit of the Stimulatory GTP Binding Protein of uch as the heart, partotid gland, and luteal cells, activation of the epidermal growth factor (EGF) receptor also stimulates second-messenger systems that involve the heterotrimeric G proteins. For instance, in the heart EGF increases contractility and heart rate by elevating cellular cyclic adenosi
Gyrate
发表于 2025-3-29 17:39:03
Regulator of Epidermal Growth Factor Signaling, expression is also induced by the epidermal growth factor receptor (EGFR) cascade in some tissues, including the follicle cells of the ovary, the wing, and eye imaginal disc, and acts to abolish mitogen-activated protein (MAP) kinase activated by EGFR signaling. Sprouty is an intracellular protein
FLIRT
发表于 2025-3-29 20:06:06
Dissecting the Epidermal Growth Factor Receptor Signal Transactivation Pathway,activation represents the so far best investigated cross-talk mechanism comprising heterogeneous receptor families. In this signaling process G protein-coupled receptor (GPCR) stimulation induces phosphorylation of the EGFR, combining the broad diversity of GPCRs with the potent signaling capacities
多山
发表于 2025-3-30 01:14:47
A Sensitive Method to Monitor Ectodomain Shedding of Ligands of the Epidermal Growth Factor Recepto from the plasma membrane. This process, which is referred to as protein ectodomain shedding, is emerging as a key regulator of the function of EGFR ligands. In light of the important roles of EGFR signaling in development and disease, it will be important to understand more about the regulation of