滔滔不绝地说
发表于 2025-3-27 00:46:25
https://doi.org/10.1007/978-3-319-49619-1uch as the heart, partotid gland, and luteal cells, activation of the epidermal growth factor (EGF) receptor also stimulates second-messenger systems that involve the heterotrimeric G proteins. For instance, in the heart EGF increases contractility and heart rate by elevating cellular cyclic adenosi
Monocle
发表于 2025-3-27 04:11:58
https://doi.org/10.1057/9780230505780 expression is also induced by the epidermal growth factor receptor (EGFR) cascade in some tissues, including the follicle cells of the ovary, the wing, and eye imaginal disc, and acts to abolish mitogen-activated protein (MAP) kinase activated by EGFR signaling. Sprouty is an intracellular protein
束缚
发表于 2025-3-27 09:19:06
https://doi.org/10.1007/978-3-030-37258-3activation represents the so far best investigated cross-talk mechanism comprising heterogeneous receptor families. In this signaling process G protein-coupled receptor (GPCR) stimulation induces phosphorylation of the EGFR, combining the broad diversity of GPCRs with the potent signaling capacities
帽子
发表于 2025-3-27 12:35:07
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离开真充足
发表于 2025-3-27 14:50:17
https://doi.org/10.1007/978-981-15-2533-9d molecule at the cell surface. Desensitization of signaling initiates when active receptors are recruited to clathrin-coated regions of the plasma membrane and subsequently sorted to intracellular degradation in lysosomes. Sorting for lysosomal degradation entails receptor conjugation with ubiquiti
法律
发表于 2025-3-27 20:43:51
https://doi.org/10.1007/978-3-322-80801-1s followed by their internalization and degradation has, in particular, been extensively studied. This chapter describes the basic methods used to measure ubiquitination and degradation of RTKs using the example of the epidermal growth factor receptor (EGFR). Common sources for endogenous and recomb
Fracture
发表于 2025-3-28 00:44:46
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好忠告人
发表于 2025-3-28 02:53:36
https://doi.org/10.1007/978-3-8350-9505-2y EGF or other high-affinity ligands often results in increased migration of cells in physiological and pathological situations. There are numerous approaches for evaluating cell migratory response following EGF stimulation. Both qualitative and quantitative techniques will be presented in this chap
平
发表于 2025-3-28 08:01:15
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有危险
发表于 2025-3-28 13:05:43
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