紧张过度
发表于 2025-3-28 15:06:16
,-Regulated Lipopolysaccharide Modificationsades such as two-component regulatory systems to detect and respond to stimuli in the local microenvironment. During infection, environmental sensing allows bacteria to regulate gene expression to evade host immune defenses and thrive in vivo. Activation of the . two-component regulatory systems Pho
Hectic
发表于 2025-3-28 20:53:03
The Variation of O Antigens in Gram-Negative Bacteriaacteria. It is on the cell surface and appears to be a major target for both immune system and bacteriophages, and therefore becomes one of the most variable cell constituents. The variability of the O antigen provides the major basis for serotyping schemes of Gram-negative bacteria. The genes respo
GLUE
发表于 2025-3-28 22:53:40
Regulators of TLR4 Signaling by Endotoxinser the past decade have revealed the components involved in these signaling pathways, however, more recently the focus has shifted somewhat towards the components that regulate these pathways. Several regulatory mechanisms, including localisation of components, splice variants and inhibitory molecul
鼓掌
发表于 2025-3-29 05:30:47
Membrane Partitioning: Is Location Everything When It Comes to Endotoxin Recognition? Lipid rafts are thought to provide a means to explain the spatial segregation of certain signalling pathways emanating from the cell surface. They seem to provide the necessary microenvironment in order for certain specialised signalling events to take place- such as the innate immune recognition.
付出
发表于 2025-3-29 11:07:43
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Limousine
发表于 2025-3-29 11:27:01
The Role of Endotoxin in Infection: , and ,l compartment and . the intestinal mucosa. Although . causes chronic gastric infection leading to gastritis, peptic ulcers and eventually gastric cancer while . causes acute infection inducing diarrhoeal disease, the endotoxin molecules of both bacterial species contrastingly contribute to their pat
增减字母法
发表于 2025-3-29 16:13:03
The Role of , Lipopolysaccharide in Cystic Fibrosis Airway Infectionwith impaired phagocytic function, such as those with burns, exposure to chemotherapy, or cystic fibrosis (CF). PA infects the lungs of most individuals with CF, and is associated with severe progressive pulmonary disease that is the major cause of premature death in this disorder. The specific adap
反叛者
发表于 2025-3-29 23:44:56
Development of Small-Molecule Endotoxin Sequestering Agentspite advances in antimicrobial chemotherapy. The primary trigger in Gram-negative sepsis is endotoxin, a lipopolysaccharide (LPS) constituent of the outer membrane of all Gram-negative bacteria. The structurally highly conserved glycolipid called lipid A is the active moiety of LPS. Lipid A is compo
向外供接触
发表于 2025-3-30 00:42:40
Development of an Anti-Endotoxin Vaccine for Sepsisin intensive care units. Vaccines directed against core LPS structures that are widely conserved among Gram-negative bacteria (GNB) have been developed for the treatment and/or prevention of sepsis. Killed whole bacterial vaccines (. O111:B4, J5 mutant and ., Re chemotype) protected m
Alveolar-Bone
发表于 2025-3-30 06:20:20
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