漂泊
发表于 2025-3-23 12:07:40
Endocannabinoid Metabolism and Transport as Drug Targets,of .-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG) in the sites where these major eCBs are indeed needed. This chapter will briefly review some preclinical and clinical evidence for the therapeutic potential of ECS pharmacological manipulation.
implore
发表于 2025-3-23 15:23:04
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地牢
发表于 2025-3-23 20:54:37
Reliability Evaluation of Power Systemson proximity assay (SPA) for PPAR α, γ, and δ. These SPAs allow to assess the binding affinities of PPAR α, γ, and δ ligands, along with their respective subtype selectivity profiles. Therefore, SPA is an important tool for hit discovery and lead optimization campaigns aimed at identifying next-generation PPAR ligands.
试验
发表于 2025-3-24 00:26:20
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Ambiguous
发表于 2025-3-24 06:19:46
Heat Generation and Dissipation,s a chemiluminescent read-out and can be performed in 384-well plates. We have successfully used this assay to characterize a set of reference ligands (both agonists, antagonists, and an inverse agonist) on human CB.R and CB.R, of which some examples will be presented here.
CHARM
发表于 2025-3-24 10:07:37
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PRE
发表于 2025-3-24 14:18:20
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得意人
发表于 2025-3-24 16:40:01
Measuring the Content of Endocannabinoid-Like Compounds in Biological Fluids: A Critical Overview ors (i.e., lipo amino acids, lipoamines, .-acyl amides) in biological fluids. Most of our focus will be on the analysis of these lipids in plasma/serum, but we will also discuss how the same techniques can be used for the analysis of saliva and breast milk.
使人烦燥
发表于 2025-3-24 20:14:21
,Scintillation Proximity Assay (SPA)-Based Radioligand Binding for PPARα, PPARγ, and PPARδ Receptorson proximity assay (SPA) for PPAR α, γ, and δ. These SPAs allow to assess the binding affinities of PPAR α, γ, and δ ligands, along with their respective subtype selectivity profiles. Therefore, SPA is an important tool for hit discovery and lead optimization campaigns aimed at identifying next-generation PPAR ligands.
Talkative
发表于 2025-3-25 01:35:50
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