flutter 发表于 2025-3-23 13:19:56

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争议的苹果 发表于 2025-3-23 17:56:40

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conquer 发表于 2025-3-23 18:00:37

,Wie demokratisch ist die Türkei?,(ed) Dose finding in drug development. Springer, New York, p 146–171, 2006) to confirm the proof of concept and identify the minimum effective dose (MED) in Phase II clinical trials was first introduced in the early 2000s. The MCP-Mod method has significantly transformed the way dose-finding studies

Fecundity 发表于 2025-3-23 23:12:50

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审问,审讯 发表于 2025-3-24 05:11:54

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功多汁水 发表于 2025-3-24 08:19:27

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调色板 发表于 2025-3-24 12:20:49

Book 2025ook details advancements made in drug development...Finding the right dose(s) is one of the most important objectives in new drug development. In Phase I clinical development, one of the objectives is to escalate test doses from low to high. The low doses should be safe, then escalate up to the maxi

落叶剂 发表于 2025-3-24 17:20:53

Adam Smith. New Intuitions For A New Age,sents a curve-free design and a hybrid design for BED-finding trials involving one agent, assuming a monotonic dose–toxicity curve and a unimodal dose–efficacy curve. The last section of the chapter provides examples and demonstrations of our Web-based R packages.

阐释 发表于 2025-3-24 19:30:15

Monotonic Dose–Response and Curve-Free Designs for Phase I Dose-Finding Trialssents a curve-free design and a hybrid design for BED-finding trials involving one agent, assuming a monotonic dose–toxicity curve and a unimodal dose–efficacy curve. The last section of the chapter provides examples and demonstrations of our Web-based R packages.

6Applepolish 发表于 2025-3-25 02:07:51

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查看完整版本: Titlebook: Dose Finding and Beyond in Biopharmaceutical Development; Jingjing Ye,Ding-Geng Chen,Joseph C. Cappelleri Book 2025 The Editor(s) (if appl