flutter 发表于 2025-3-23 13:19:56
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,Wie demokratisch ist die Türkei?,(ed) Dose finding in drug development. Springer, New York, p 146–171, 2006) to confirm the proof of concept and identify the minimum effective dose (MED) in Phase II clinical trials was first introduced in the early 2000s. The MCP-Mod method has significantly transformed the way dose-finding studiesFecundity 发表于 2025-3-23 23:12:50
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Book 2025ook details advancements made in drug development...Finding the right dose(s) is one of the most important objectives in new drug development. In Phase I clinical development, one of the objectives is to escalate test doses from low to high. The low doses should be safe, then escalate up to the maxi落叶剂 发表于 2025-3-24 17:20:53
Adam Smith. New Intuitions For A New Age,sents a curve-free design and a hybrid design for BED-finding trials involving one agent, assuming a monotonic dose–toxicity curve and a unimodal dose–efficacy curve. The last section of the chapter provides examples and demonstrations of our Web-based R packages.阐释 发表于 2025-3-24 19:30:15
Monotonic Dose–Response and Curve-Free Designs for Phase I Dose-Finding Trialssents a curve-free design and a hybrid design for BED-finding trials involving one agent, assuming a monotonic dose–toxicity curve and a unimodal dose–efficacy curve. The last section of the chapter provides examples and demonstrations of our Web-based R packages.6Applepolish 发表于 2025-3-25 02:07:51
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